Questões de USMLE

3.602 questões com gabarito e explicação.

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A 58-year-old man with type 2 diabetes (HbA1c 9.2%, fasting glucose 187 mg/dL) presents for cost analysis study enrollment. Linear regression models his HbA1c versus annual healthc
A 41 year old man with long standing intravenous drug use dies of infective endocarditis. In the same city, an 84 year old woman dies of heart failure. Public health officials emph
A randomized controlled trial enrolls 500 healthy adults (mean age 35) during winter. Symptomatic, PCR-confirmed influenza develops in 10% of placebo recipients and 5% of vaccine r
A psychiatry research group develops a novel 12-item anhedonia scale in 200 patients with major depressive disorder (mean age 42, BP 128/82, HR 88) and 100 healthy controls (BP 120
A Phase III trial randomizes 300 participants with stage III non-small cell lung cancer in a 2:1 ratio (200 to new tyrosine kinase inhibitor versus 100 to standard chemotherapy). B
A propensity-matched observational study compares beta-blocker therapy versus no beta-blocker after myocardial infarction in 500 post-MI patients. After matching, investigators rep
A 58-year-old man with type 2 diabetes mellitus presents for device validation testing. Blood pressure is 138/82 mmHg, heart rate 76/min, temperature 37.2°C. A fasting glucose obta
A 35-year-old woman on oral contraceptives presents with left leg swelling, pain, and warmth. Vital signs show BP 118/76, HR 92, RR 16, temp 37°C, SpO2 98%. Doppler ultrasound conf
A longitudinal diabetes study has intermittent missing hemoglobin A1c values because some patients miss clinic appointments but later return. Investigators use patients' prior A1c
A hospital initiates annual low-dose CT screening for high-risk smokers (age 55-75, ≥30 pack-years). Five years later, screened patients (BP 138/82, HR 78, RR 16, SpO2 98%) demonst
A county health department follows 20,000 residents for 1 year after a contaminated water exposure. At baseline, 200 residents already have documented immunity to hepatitis A from
A 4 month old infant with no prior vaccinations is brought to clinic because of paroxysmal coughing spells followed by inspiratory whooping and posttussive vomiting. The responsibl
An investigator is studying the immunologic response to a Staphylococcus aureus toxin in a mouse model. Fourteen days after injecting mice with this toxin, he isolates antibodies a
A chemoprophylaxis regimen is administered to household contacts during a meningococcal outbreak. Baseline vital signs are stable; temperature 37.2°C, HR 88/min, BP 118/76 mmHg. Ce
A 7 year old boy is seen for recurrent skin abscesses and repeated episodes of pneumonia. His parents say the abscesses are not very red or tender. He has chronic eczema and coarse
A 23 year old woman comes to the emergency department with recurrent episodes of severe abdominal pain and swelling of the lips and tongue. She has no urticaria or pruritus. Sympto
A regression model evaluates the effect of obesity on obstructive sleep apnea severity in 250 adults (mean BMI 34 kg/m², apnea-hypopnea index 28 events/hour). Investigators include
A 65-year-old man with a past medical history of well-controlled hypertension on lisinopril presents for annual preventive care. He reports feeling well with no acute complaints. V
A 5 year old girl is evaluated for recurrent pyogenic infections and progressive difficulty walking. Her parents report that she bruises easily and that her hair and skin have alwa
A 45-year-old woman with chronic migraines (BP 128/82, HR 82, previously on topiramate) enrolls in a crossover trial comparing two prophylactic medications. After completing the fi
A 58 year old man comes to clinic for evaluation of intermittent hematochezia and a 4 kg unintentional weight loss. Before ordering colonoscopy, investigators studying a fecal immu
A 76-year-old woman presents to the clinic with a 2-month history of temporal headaches, scalp tenderness, and jaw claudication while chewing. She reports amaurosis fugax of the ri
A health system evaluates whether a text message reminder program reduces missed insulin follow-up visits among adults with type 2 diabetes (mean age 58 years). The intervention is
A 23-year-old male college student presents with a 6-month history of excessive daytime somnolence despite obtaining 7–8 hours of nocturnal sleep. He reports sudden, irresistible e
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