A 76-year-old woman presents to the clinic with a 2-month history of temporal headaches, scalp tenderness, and jaw claudication while chewing. She reports amaurosis fugax of the right eye lasting 10 minutes this morning. On examination, she has limited shoulder abduction and hip flexion bilaterally due to pain and stiffness. Laboratory studies show an erythrocyte sedimentation rate of 68 mm/h and a hemoglobin of 9.8 g/dL. Temporal artery biopsy confirms the suspected diagnosis. High-dose corticosteroid therapy is initiated. Which of the following laboratory findings would be expected as a direct consequence of corticosteroid treatment?

  1. A)Decreased lymphocytes, decreased neutrophils, decreased eosinophils, and decreased fibroblasts
  2. B)Increased lymphocytes, increased neutrophils, decreased eosinophils, and increased fibroblasts
  3. C)Decreased lymphocytes, increased neutrophils, increased eosinophils, and increased fibroblasts
  4. D)Decreased lymphocytes, decreased neutrophils, increased eosinophils, and decreased fibroblasts
  5. E)Decreased lymphocytes, increased neutrophils, decreased eosinophils, and decreased fibroblastsGABARITO

Explicação

The clinical presentation describes giant cell (temporal) arteritis, which is treated with high-dose corticosteroids. Glucocorticoids produce a characteristic pattern of leukocyte changes: lymphocyte suppression (via T-cell apoptosis and redistribution from ci... Ver explicação completa e trilha adaptativa →

Fazer o diagnóstico grátis de USMLE