Questões de USMLE
3.602 questões com gabarito e explicação.
Fazer o diagnóstico grátisA 2 month old boy has recurrent viral and fungal infections, difficulty feeding, and episodes of perioral twitching. He was born with a conotruncal cardiac defect. Physical examina…
An 8 year old boy is brought to the physician because of frequent ear infections and progressive difficulty walking. His parents report that he often stumbles and has had several e…
A 6-year-old boy with sickle cell disease presents with fever (39.2°C), lethargy, and nuchal rigidity. Vital signs show HR 128/min, RR 28/min, BP 102/68 mmHg, and SpO2 98% on room …
A 17 year old boy is evaluated for recurrent sinusitis and chronic watery diarrhea. He has had two prior episodes of Giardia lamblia infection. He is otherwise healthy. Serum immun…
A rapid screening test for celiac disease has the same sensitivity and specificity in all populations. A family medicine clinic uses the test in asymptomatic adults, whereas a gast…
A 72-year-old man with newly diagnosed pancreatic cancer presents with jaundice, weight loss of 8 kg over 2 months, and epigastric pain. Vital signs: BP 118/76, HR 92, RR 18, Temp …
A 27-year-old man presents with fever (39.2°C), cough, and dyspnea. Vital signs show BP 118/76, HR 102, RR 22, SpO2 88% on room air. Chest X-ray reveals bilateral infiltrates. Bloo…
A 7 month old infant has chronic diarrhea, oral candidiasis, and recurrent viral and bacterial respiratory infections. Flow cytometry shows normal B cell count, low CD4 positive T …
A randomized controlled trial enrolls 500 healthy adults (mean age 35) during winter. Symptomatic, PCR-confirmed influenza develops in 10% of placebo recipients and 5% of vaccine r…
A longitudinal diabetes study has intermittent missing hemoglobin A1c values because some patients miss clinic appointments but later return. Investigators use patients' prior A1c …
Investigators are designing an observational study comparing fracture risk in chronic glucocorticoid users and nonusers. They are particularly concerned that age and sex differ sub…
A team develops a questionnaire to measure asthma control in adolescents. Pediatric pulmonologists review the draft noting it includes wheeze frequency and rescue inhaler use but o…
Investigators study a possible association between a pesticide and Parkinson disease. They enroll 120 patients with Parkinson disease and 200 controls without Parkinson disease. Am…
A new antiviral medication is introduced for a chronic infection in a city of 1 million people. The drug does not prevent new infections, but it markedly shortens the duration of s…
A 30 year old primigravid woman experiences an intrauterine fetal demise at 32 weeks' gestation. In the same hospital that year, there are 8 late fetal deaths and 12 neonatal death…
A nested case control study of venous thromboembolism is conducted within a large cohort of women using oral contraceptives. Each time a new thrombosis case occurs, controls are se…
A 52-year-old woman with rheumatoid arthritis (ESR 48 mm/h, CRP 12 mg/L) presenting with joint pain and morning stiffness is screened for a biologic therapy trial. She has no histo…
A 29-year-old woman presents with severe vaginal bleeding and hypotension (BP 80/50, HR 120, RR 22) two days after vaginal delivery of her second child. Despite aggressive fluid re…
A 63-year-old man with acute ST-elevation myocardial infarction (BP 128/82, HR 102, RR 18, SpO2 98%) presents with elevated troponin I (2.8 ng/mL) and anterior wall changes on ECG.…
A 58-year-old man with type 2 diabetes (HbA1c 9.2%, fasting glucose 187 mg/dL) presents for cost analysis study enrollment. Linear regression models his HbA1c versus annual healthc…
A randomized controlled trial evaluating a new antihypertensive medication requires all participants to complete a 2-week placebo run-in phase before randomization. Patients presen…
A 58-year-old man with type 2 diabetes mellitus presents for device validation testing. Blood pressure is 138/82 mmHg, heart rate 76/min, temperature 37.2°C. A fasting glucose obta…
A 35-year-old woman on oral contraceptives presents with left leg swelling, pain, and warmth. Vital signs show BP 118/76, HR 92, RR 16, temp 37°C, SpO2 98%. Doppler ultrasound conf…
A randomized trial of a new asthma medication in 400 patients shows no difference in FEV1 decline (primary endpoint: -120 mL/year in both groups; p=0.18). Investigators perform 40 …