A 63-year-old man with acute ST-elevation myocardial infarction (BP 128/82, HR 102, RR 18, SpO2 98%) presents with elevated troponin I (2.8 ng/mL) and anterior wall changes on ECG. He has type 2 diabetes mellitus managed with metformin but denies prior cardiac events. Investigators enrolling him in a novel antiplatelet drug trial separate participants into diabetic and nondiabetic groups before randomizing within each stratum. Which study design best describes this method?

  1. A)Allocation concealment
  2. B)Cluster randomization
  3. C)Stratified randomizationGABARITO
  4. D)Matching
  5. E)Block randomization

Explicação

Stratified randomization separates participants by an important prognostic variable and then randomizes within each stratum. This helps ensure treatment groups remain balanced for factors such as diabetes that could strongly influence outcome. It improves comp... Ver explicação completa e trilha adaptativa →

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