Questões de USMLE

A 45-year-old woman participates in a randomized influenza vaccine trial. She receives the inactivated influenza vaccine and remains asymptomatic throughout the season with normal …

A tropical region has consistently reported 15 to 20 malaria cases per 100,000 people annually for over a decade with minimal year-to-year variation. Recent surveillance data confi…

A 7-year-old boy with acute lymphoblastic leukemia currently receiving chemotherapy (HR 102, BP 98/62, temp 37.2°C) has an absolute neutrophil count of 800/μL and cannot receive li…

A 15-year prospective cohort study enrolls 5,000 asymptomatic adults aged 40-60 years and follows them for cardiovascular disease (CVD) outcomes. Baseline measurements include tota…

A 45-year-old woman with no significant medical history presents for routine breast cancer screening mammography. The examination is interpreted as BI-RADS 4 (suspicious for malign…

A tropical region in Southeast Asia has consistently reported 15 to 20 malaria cases per 100,000 people annually for the past 8 years with minimal year-to-year variation. Serologic…

A 52-year-old woman presents with weight loss and palpitations. Vital signs: BP 142/88, HR 108, RR 18, Temp 37.2°C, SpO2 98%. Laboratory studies show elevated free T4 (28 pg/mL) an…

A 7 year old boy is diagnosed with acute lymphoblastic leukemia, and investigators design a case control study to evaluate household benzene exposure. They match each case to contr…

A screening program for colorectal cancer detects 95% of cases in people with the disease and correctly identifies 90% of people without the disease as disease-free. In the general…

A researcher compares crude mortality rates between a retirement community (mean age 78 years) and a nearby university town (mean age 22 years). The retirement community demonstrat…

A 78-year-old man with advanced dementia presents to the ED in respiratory distress. Vital signs: BP 128/76, HR 102, RR 28, SpO2 78% on room air. Chest X-ray shows bilateral infilt…

A 32-year-old female presents with left leg swelling and pain. She uses oral contraceptives and smokes one pack daily. Vital signs: BP 118/76, HR 92, RR 16, Temp 37°C, SpO2 98%. D-…

A state epidemiologist is reviewing surveillance data for pertussis (Bordetella pertussis infection) across a region. The reported incidence increased from 4 cases per 100,000 popu…

Researchers conduct a study to evaluate the effectiveness of a newly licensed rotavirus vaccine in a developing country. They vaccinate 8,000 children aged 6-24 months in a rural d…

A 72-year-old man with stage IV pancreatic cancer and progressive cognitive decline from brain metastases is admitted to the hospital with sepsis. He is currently alert but increas…

A 52-year-old man with a 30-pack-year smoking history presents with BP 138/86, HR 82, RR 16, and SpO2 98% on room air. He denies dyspnea, cough, or chest pain. Spirometry shows FEV…

A 62-year-old man with 45 pack-year smoking history presents for routine follow-up. CT chest screening reveals a 1.2-cm nodule (Lung-RADS 3); PET-CT shows no hypermetabolic activit…

A 14-year-old boy is brought to the office by his mother after she discovered a marijuana cigarette in his bedroom. The mother is very concerned and worried this indicates her son …

A randomized controlled trial comparing two antihypertensive agents (amlodipine vs. lisinopril) enrolls 300 patients with Stage 2 hypertension. Patients are randomized 1:1 using a …

A prospective cohort study follows 200 night-shift workers and 400 day-shift workers for 5 years to assess new onset hypertension. By the end of follow up, 40 night-shift workers a…

A 42-year-old woman with obesity (BMI 34 kg/m²) presents for metabolic evaluation. Vital signs: BP 138/82 mmHg, HR 88 bpm, RR 14/min, temp 37°C. Fasting insulin is 18 mIU/L. Resear…

A residency program introduces a sepsis checklist intervention across 10 hospitals, with each site randomly assigned a staggered implementation month over 12 months. Baseline sepsi…

A rapid screening test for celiac disease has the same sensitivity and specificity in all populations. A family medicine clinic uses the test in asymptomatic adults, whereas a gast…

A 72-year-old man with newly diagnosed pancreatic cancer presents with jaundice, weight loss of 8 kg over 2 months, and epigastric pain. Vital signs: BP 118/76, HR 92, RR 18, Temp …