Questões de USMLE

3.602 questões com gabarito e explicação.

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A 45 year old woman has chronic watery diarrhea, episodic flushing, and a 6 month history of worsening confusion and hyperpigmented scaling on sun exposed areas of her hands and ne
A 3 year old boy is brought in for developmental delay and involuntary writhing movements. He has a history of self mutilation with biting of his lips and fingers. Orange sand like
A 61-year-old woman with hyperlipidemia presents with corneal opacities and tendon xanthomas. Her lipid panel shows total cholesterol 520 mg/dL, LDL 380 mg/dL, and HDL 45 mg/dL. Sh
A 3-month-old girl presents with poor feeding and weak crying. Vital signs show HR 152, RR 38, BP 78/52, temp 37°C, SpO2 98% on room air. Examination reveals marked hypotonia and h
A 50-year-old male was admitted into the hospital of a leading research university with a diagnosis of hepatitis and early cirrhosis of the liver. His past medical history is signi
A 6 year old boy is brought to the pediatrician after a routine school urine screen shows a positive test for reducing substances. He has no abdominal pain, vomiting, or developmen
A 9 month old boy is evaluated for vomiting, diaphoresis, and lethargy that occur shortly after fruit puree is introduced into his diet. His parents report that he was previously w
A 5-day-old female newborn develops jaundice, poor feeding, and vomiting after breastfeeding. She becomes lethargic and is admitted to the NICU. Vital signs show temperature 37.2°C
A 2 month old boy has poor feeding, tachypnea, and developmental delay. He has intermittent ataxia and hypotonia. Laboratory studies show elevated serum lactate and pyruvate, but h
A 7 year old boy is evaluated for chronic jaundice and fatigue. He has scleral icterus and splenomegaly. Laboratory studies show hemoglobin 8.8 g per dL, elevated indirect bilirubi
A 13-year-old boy presents with progressive fatigue, easy bruising, and recurrent bone pain over 6 months. Vital signs show BP 105/68, HR 92, RR 18, temp 37.2°C, SpO2 98%. Examinat
A 52 year old woman with metastatic renal cell carcinoma enrolls in a trial of a drug that irreversibly binds an allosteric site on a signaling enzyme and reduces its catalytic act
A 2-day-old female newborn presents with vomiting, tachypnea (RR 58/min), and progressive somnolence. Vital signs show HR 168/min, BP 65/40 mmHg, temperature 36.8°C, SpO2 98% on ro
A 19-year-old man presents with severe muscle cramps and early fatigue during sprinting and weightlifting. He reports dark urine after intense exercise. Vital signs at rest are nor
A 10-month-old boy presents with progressive developmental regression and an exaggerated startle response over the past 2 months. Vital signs: HR 118/min, RR 28/min, Temp 37.2°C. F
A 1-year-old girl presents with developmental regression, abdominal distention, and failure to thrive. Vital signs show HR 110/min, RR 28/min, temp 37.2°C. Physical examination rev
A 4-day-old female newborn presents with poor feeding, vomiting, hypotonia, and seizures. Vital signs reveal HR 155 bpm, RR 28/min, temp 37.2°C. Laboratory studies demonstrate high
A 6-day-old male newborn presents with poor feeding, vomiting, and alternating hypotonia and hypertonia with intermittent opisthotonos. Vital signs reveal HR 148/min, RR 32/min, an
A 7-month-old boy presents with failure to thrive and pallor. Vital signs show HR 128/min, RR 22/min, Temp 37.2°C. Laboratory studies reveal hemoglobin 7.2 g/dL with megaloblastic
A 23 year old man develops jaundice and dark urine 2 days after starting trimethoprim sulfamethoxazole for a skin infection. He had a similar episode after eating fava beans. Labor
A 30-year-old vegetarian male presents with progressive paresthesias in his lower extremities and gait disturbance over 6 months. He has followed a strict meat-free diet for 15 yea
A 63 year old woman presents with fatigue, numbness in her feet, and difficulty walking. Examination shows decreased vibration sense in both legs and a smooth beefy red tongue. Lab
A 4-month-old male presents with recurrent oral thrush, chronic diarrhea, and recurrent severe respiratory infections. Vital signs show HR 128/min, RR 32/min, temperature 37.2°C, S
A 4-year-old girl presents with progressive gait instability and loss of speech over 6 months. Vital signs show BP 98/62, HR 102, RR 22, temp 37.2°C, SpO2 98%. Neurologic examinati
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