A 45 year old woman has chronic watery diarrhea, episodic flushing, and a 6 month history of worsening confusion and hyperpigmented scaling on sun exposed areas of her hands and neck. Urine 5 HIAA is markedly elevated. Deficiency of which vitamin is most likely contributing to her rash and neuropsychiatric symptoms?
- A)Vitamin B1
- B)Vitamin B2
- C)Vitamin B12
- D)Vitamin B3GABARITO
- E)Vitamin B6
Explicação
Carcinoid syndrome can divert tryptophan toward serotonin synthesis, decreasing niacin production and causing pellagra. Niacin deficiency classically causes the three Ds: diarrhea, dermatitis, and dementia. The flushing and elevated 5 HIAA point to a serotonin... Ver explicação completa e trilha adaptativa →