A 17-year-old boy with mild hemophilia A presents for dental extraction. Vital signs are stable: BP 120/78 mmHg, HR 82/min, RR 16/min, temp 37°C. Laboratory studies show factor VIII activity 35% (normal >50%). His hematologist administers a medication that increases release of von Willebrand factor and factor VIII from endothelial storage sites. The patient denies previous adverse reactions to hemostatic agents. Which drug was most likely administered?
- A)Hydrocortisone
- B)Tolvaptan
- C)Oxytocin
- D)Octreotide
- E)DesmopressinGABARITO
Explicação
Desmopressin is not only an ADH analog for central diabetes insipidus but also increases release of von Willebrand factor and factor VIII. That makes it useful for von Willebrand disease and mild hemophilia A before procedures. Ver explicação completa e trilha adaptativa →