A 49-year-old woman with acromegaly treated with somatostatin analog therapy demonstrates improved headaches and soft tissue swelling. Six months into treatment, she presents with episodic right upper quadrant pain and fever (38.2°C). Vital signs show BP 128/82, HR 88, RR 16. Abdominal ultrasound reveals multiple gallstones with no common bile duct dilation. LFTs are normal. She denies prior biliary disease. Which medication is most likely responsible for cholelithiasis?

  1. A)OctreotideGABARITO
  2. B)Semaglutide
  3. C)Pegvisomant
  4. D)Cabergoline
  5. E)Leuprolide

Explicação

Octreotide is a somatostatin analog and can impair gallbladder contractility, predisposing to gallstone formation. The combination of medical treatment for acromegaly and subsequent cholelithiasis strongly suggests this drug. Ver explicação completa e trilha adaptativa →

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