A 12-year-old boy presents with a heart murmur detected on routine examination. Vital signs show BP 110/72 mmHg, HR 88 bpm, RR 18/min, temperature 37°C, and SpO2 98% on room air. Physical examination reveals a fixed split S2 that does not vary with respiration. Chest X-ray shows mild cardiomegaly. Transthoracic echocardiography confirms a secundum atrial septal defect with a 15-mm defect size and normal left ventricular function. He denies dyspnea on exertion. Which mechanism best explains the fixed splitting of S2?

  1. A)Right ventricular stroke volume remains persistently increased throughout the respiratory cycleGABARITO
  2. B)Inspiration equally increases both left and right ventricular filling
  3. C)Pulmonic valve closure is fixed early because pulmonary artery pressure is low
  4. D)The aortic valve closes late due to left ventricular outflow obstruction
  5. E)The murmur is generated by turbulence across the septal defect itself

Explicação

In an ASD, left to right shunting causes chronically increased right ventricular filling and a persistently prolonged right ventricular ejection time. Because the right sided volume load remains elevated regardless of respiratory phase, splitting of S2 becomes... Ver explicação completa e trilha adaptativa →

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