A 62-year-old woman with a history of systemic sclerosis presents with acute kidney injury, hypertension (200/120 mmHg), and microangiopathic hemolytic anemia. Serum creatinine increased from 1.0 to 3.2 mg/dL over 3 days. Kidney biopsy shows acute tubular necrosis and thrombotic microangiopathy. Which of the following is the most likely diagnosis?
- A)Scleroderma renal crisisGABARITO
- B)Anti-GBM disease
- C)Preeclampsia
- D)Thrombotic thrombocytopenic purpura
- E)Hemolytic uremic syndrome
Explicação
Scleroderma renal crisis is a medical emergency presenting with sudden severe hypertension, acute renal failure, and thrombotic microangiopathy in systemic sclerosis patients, especially with early diffuse cutaneous disease. Pathophysiology involves renin-medi... Ver explicação completa e trilha adaptativa →