A 41-year-old HIV-positive man with CD4 count of 85 cells/μL presents with fever (38.9°C), headache, and neck stiffness for 2 weeks. Vital signs show BP 110/70 mmHg, HR 98/min, RR 18/min, SpO2 98% on room air. CSF analysis demonstrates elevated protein (120 mg/dL), low glucose (25 mg/dL), negative bacterial culture, and India ink staining positive for encapsulated yeast. No focal neurologic deficits are appreciated. Which organism is most likely responsible?
- A)Histoplasmal meningitis
- B)Aspergillal meningitis
- C)Coccidioidal meningitis
- D)Pneumocystis meningitis
- E)Cryptococcal meningitisGABARITO
Explicação
Cryptococcus neoformans causes meningitis in severely immunocompromised HIV patients (CD4 <50-100). CSF shows lymphocytic pleocytosis with elevated protein and low glucose. India ink staining demonstrates round yeast with characteristic halo (polysaccharide ca... Ver explicação completa e trilha adaptativa →