In the family shown below, individuals affected with profound deafness are represented by a shaded symbol. (Pedigree shows two couples in generation I and II with normal hearing producing a deaf child in generation III, along with other affected individuals.) Which of the following would best explain the phenotypes of individuals in the fourth generation?

1. A)X-linked dominant inheritance
2. B)Autosomal dominant inheritance
3. C)Locus heterogeneityGABARITO
4. D)Mitochondrial inheritance
5. E)Multifactorial inheritance