A 26 year old man travels from Boston to a ski resort in Colorado at 3200 meters above sea level. On the first day he develops headache and tachypnea. Two days later his tissues are extracting oxygen more effectively despite the lower ambient oxygen tension. Which of the following best explains the later improvement in tissue oxygen delivery?
- A)Increased 2,3 bisphosphoglycerate in erythrocytesGABARITO
- B)Decreased hypoxic pulmonary vasoconstriction
- C)Decreased 2,3 bisphosphoglycerate in erythrocytes
- D)Decreased minute ventilation due to renal compensation
- E)Increased surfactant production by type I pneumocytes
Explicação
Increased 2,3 bisphosphoglycerate in erythrocytes is correct. At high altitude, hypoxemia stimulates hyperventilation immediately and over time erythrocytes increase 2,3 bisphosphoglycerate, shifting the oxygen hemoglobin dissociation curve to the right and fa... Ver explicação completa e trilha adaptativa →