A 67-year-old man with a 3-month history of progressive weight loss and epigastric pain radiating to the back presents with painless jaundice. Vital signs: BP 128/82, HR 94, RR 16, Temp 37.2°C, SpO2 98%. CT reveals a 3-cm hypoattenuating mass in the pancreatic head. Labs show total bilirubin 8.2 mg/dL with direct predominance; alkaline phosphatase elevated at 320 U/L. Notably, he denies alcohol use. Which serum marker best monitors disease burden in this malignancy?
- A)Cancer antigen 125
- B)Cancer antigen 15-3
- C)Beta human chorionic gonadotropin
- D)Neuron specific enolase
- E)Cancer antigen 19-9GABARITO
Explicação
CA 19-9 is the tumor marker most commonly used to monitor pancreatic adenocarcinoma. It is not ideal for screening, but trends can help follow response or recurrence in a known case. Ver explicação completa e trilha adaptativa →