A 27 year old man comes to the emergency department with hemoptysis, dark urine, and fatigue for 5 days. He has blood pressure of 168/98 mm Hg and mild periorbital edema. Urinalysis shows dysmorphic red blood cells and red blood cell casts. Serum creatinine is markedly elevated. Kidney biopsy is most likely to show which of the following findings?
- A)Nodular mesangial expansion with arteriolar hyalinosis
- B)Mesangial IgA deposition following mucosal infection
- C)Effacement of podocyte foot processes on electron microscopy
- D)Linear IgG and C3 deposition along the glomerular basement membrane with crescentsGABARITO
- E)Subepithelial immune complex deposits with a spike and dome appearance
Explicação
This patient has rapidly progressive glomerulonephritis due to anti glomerular basement membrane disease, also called Goodpasture syndrome. The combination of hemoptysis and nephritic urine sediment points to anti GBM antibodies that produce linear immunofluor... Ver explicação completa e trilha adaptativa →