A 76 year old man presents with exertional dyspnea and syncope. Cardiac examination reveals a late peaking systolic crescendo decrescendo murmur at the right upper sternal border radiating to the carotids. Serum calcium and phosphorus are normal. Surgical pathology of the excised valve shows irregular basophilic calcium deposits within fibrotic valve leaflets. Which of the following is the most likely process?
- A)Metastatic calcification
- B)Amyloid deposition
- C)Dystrophic calcificationGABARITO
- D)Osseous metaplasia
- E)Cholesterol cleft formation
Explicação
Dystrophic calcification is calcium deposition in injured or necrotic tissue in the setting of normal serum calcium. This patient has calcific aortic stenosis with chronic valvular damage, making dystrophic calcification the correct pathologic process. Ver explicação completa e trilha adaptativa →