A 55-year-old man with chronic hepatitis C infection presents with peripheral edema and hematuria. Vital signs show BP 158/94 mmHg, HR 88/min, RR 16/min, and temperature 37.2°C. Urinalysis reveals dysmorphic RBCs and proteinuria (2.8 g/24h). Serum complement C4 level is markedly decreased at 8 mg/dL (normal 15-45), and cryoglobulins are detected in serum. Chest examination is clear to auscultation. Which glomerular disease is most likely?
- A)Membranoproliferative glomerulonephritisGABARITO
- B)Diabetic nephropathy
- C)Membranous nephropathy
- D)FSGS
- E)Minimal change disease
Explicação
Hepatitis C is strongly associated with mixed cryoglobulinemia and membranoproliferative glomerulonephritis. The combination of hematuria, proteinuria, low complement, and cryoglobulins is highly characteristic. Ver explicação completa e trilha adaptativa →