A 52-year-old man with resistant hypertension uncontrolled on lisinopril and hydrochlorothiazide is started on a centrally acting sympatholytic agent at 0.1 mg twice daily. Two weeks later, he presents with dry mouth, daytime somnolence, and mild bradycardia (HR 58/min). Current vital signs show BP 128/76 mmHg, temperature 37.1°C, and RR 14/min. Physical examination reveals mildly reduced salivation and no peripheral edema. Laboratory studies reveal normal electrolytes and renal function. He denies orthostatic symptoms. Which medication was most likely prescribed?
- A)Phenoxybenzamine
- B)Metoprolol
- C)ClonidineGABARITO
- D)Hydralazine
- E)Prazosin
Explicação
Clonidine is a central alpha 2 agonist that lowers blood pressure by decreasing sympathetic outflow. Sedation and dry mouth are classic adverse effects of this mechanism. Ver explicação completa e trilha adaptativa →