A 67-year-old man treated with a class III antiarrhythmic for recurrent ventricular tachycardia presents with progressive dyspnea and cough over six months. Vital signs show HR 78/min, BP 138/92 mmHg, RR 22/min, SpO2 92% on room air. Physical examination reveals blue-gray skin discoloration and photosensitivity. Laboratory studies show elevated transaminases (AST 145 U/L). Chest X-ray demonstrates pulmonary fibrosis. He denies orthopnea. Which antiarrhythmic drug most likely caused these findings?
- A)Quinidine
- B)Sotalol
- C)AmiodaroneGABARITO
- D)Lidocaine
- E)Diltiazem
Explicação
Amiodarone is a class III antiarrhythmic associated with pulmonary fibrosis, hepatotoxicity, thyroid dysfunction, corneal deposits, photosensitivity, and blue-gray skin changes. The constellation of pulmonary and dermatologic toxicity in a patient treated for ... Ver explicação completa e trilha adaptativa →