A 55-year-old woman with no significant past medical history presents to the emergency department with acute right lower quadrant pain, fever, and elevated WBC. CT imaging confirms acute appendicitis, and she is scheduled for an emergent laparoscopic appendectomy. The surgical team implements a standardized WHO surgical safety checklist that includes: (1) pre-operative team briefing with patient identity and procedure verification, (2) surgical site marking by the surgeon, and (3) a formal time-out pause immediately before incision where all team members confirm patient identity, procedure, and site. Multiple high-quality studies have demonstrated that systematic implementation of this checklist significantly improves patient outcomes. Which of the following metrics would best evaluate whether this intervention is achieving its intended effect on reducing patient harm?

1. A)Reduction in never events (such as wrong-site surgery or retained surgical objects) and surgical site infectionsGABARITO
2. B)Decreased operative time and increased number of surgical cases completed per operative day
3. C)Increased patient satisfaction scores and reduced time from admission to surgical incision
4. D)Reduced anesthesia complications and lower rates of perioperative blood transfusions
5. E)Improved surgeon efficiency metrics and decreased hospital length of stay