A 21-year-old man presents with intermittent scleral icterus exacerbated by fasting and stress. Vital signs: BP 118/76, HR 82, RR 16, Temp 37°C, SpO2 98%. He denies abdominal pain and reports no weight loss. Physical examination reveals mild jaundice without hepatomegaly or splenomegaly. Laboratory studies show total bilirubin 3.2 mg/dL with unconjugated predominance; AST, ALT, and alkaline phosphatase are normal. Hemoglobin 14.2 g/dL. Which of the following is the most likely diagnosis?
- A)Acute viral hepatitis
- B)Choledocholithiasis
- C)Gilbert syndromeGABARITO
- D)Dubin-Johnson syndrome
- E)Crigler-Najjar syndrome type I
Explicação
Gilbert syndrome is a benign condition caused by mildly decreased UDP-glucuronosyltransferase activity leading to mild intermittent unconjugated hyperbilirubinemia. Ver explicação completa e trilha adaptativa →