A 21-year-old man presents with intermittent scleral icterus exacerbated by fasting and stress. Vital signs: BP 118/76, HR 82, RR 16, Temp 37°C, SpO2 98%. He denies abdominal pain and reports no weight loss. Physical examination reveals mild jaundice without hepatomegaly or splenomegaly. Laboratory studies show total bilirubin 3.2 mg/dL with unconjugated predominance; AST, ALT, and alkaline phosphatase are normal. Hemoglobin 14.2 g/dL. Which of the following is the most likely diagnosis?

  1. A)Acute viral hepatitis
  2. B)Choledocholithiasis
  3. C)Gilbert syndromeGABARITO
  4. D)Dubin-Johnson syndrome
  5. E)Crigler-Najjar syndrome type I

Explicação

Gilbert syndrome is a benign condition caused by mildly decreased UDP-glucuronosyltransferase activity leading to mild intermittent unconjugated hyperbilirubinemia. Ver explicação completa e trilha adaptativa →

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