A 61-year-old woman with amyotrophic lateral sclerosis presents with progressive lower extremity weakness over 8 months. Vital signs: BP 128/76, HR 88, RR 18, SpO2 98% on room air. EMG shows denervation potentials in multiple myotomes. She denies cognitive changes. Currently takes only lisinopril for hypertension. Her neurologist prescribes a medication that decreases glutamate-mediated excitotoxicity and modestly prolongs survival. Which drug was most likely prescribed?
- A)RiluzoleGABARITO
- B)Interferon beta
- C)Pyridostigmine
- D)Edrophonium
- E)Levodopa
Explicação
Riluzole is used in ALS and is thought to reduce glutamate mediated excitotoxic neuronal injury. It modestly prolongs survival in a disease characterized by degeneration of upper and lower motor neurons. Ver explicação completa e trilha adaptativa →