A premature newborn (32 weeks gestation) presents with tachypnea (RR 68/min), poor weight gain, and feeding intolerance. Vital signs show BP 55/35 mmHg, HR 165/min, SpO2 98% on room air, and normal temperature. Cardiac examination reveals a continuous "machine-like" murmur at the left infraclavicular region. Chest X-ray demonstrates pulmonary edema and cardiomegaly. No hepatomegaly is noted on examination. Which medication would most likely promote closure of the patent ductus arteriosus?
- A)Milrinone
- B)Prostaglandin E1 infusion
- C)Furosemide
- D)IndomethacinGABARITO
- E)Dobutamine
Explicação
Patent ductus arteriosus is maintained by prostaglandins and is common in premature infants. Indomethacin, an NSAID, lowers prostaglandin synthesis and promotes ductal closure. The continuous machine like murmur is the classic clue. Ver explicação completa e trilha adaptativa →