A 58 year old man presents with 8 months of progressive weakness in his hands and legs. He has muscle cramps and fasciculations. Examination shows atrophy of the intrinsic hand muscles, brisk reflexes at the knees, spasticity in the legs, and no sensory deficits. Which of the following is the most likely diagnosis?
- A)Guillain Barre syndrome
- B)Multiple sclerosis
- C)Amyotrophic lateral sclerosisGABARITO
- D)Myasthenia gravis
- E)Polymyositis
Explicação
Amyotrophic lateral sclerosis is correct. ALS is characterized by combined upper and lower motor neuron degeneration involving the corticospinal tracts and anterior horn cells, producing weakness, atrophy, fasciculations, hyperreflexia, and spasticity without ... Ver explicação completa e trilha adaptativa →