A 58-year-old male sandblaster with 30-year exposure history presents with progressive dyspnea, cough, and chest tightness over 6 months. Vital signs: BP 138/88 mmHg, HR 102/min, RR 22/min, SpO2 88% on room air. Chest X-ray reveals upper lobe nodular opacities with eggshell calcification of hilar lymph nodes. Pulmonary function tests show reduced FEV1/FVC ratio. He denies hemoptysis. He takes only albuterol PRN. Which additional complication is most strongly associated with this occupational exposure?
- A)Pulmonary hemorrhage from anti type IV collagen antibodies
- B)Bronchiolitis obliterans after lung transplantation
- C)Pleural mesothelioma due to amphibole fibers
- D)Pulmonary infection with Mycobacterium tuberculosisGABARITO
- E)Peripheral adenocarcinoma of the lung in never smokers
Explicação
Pulmonary infection with Mycobacterium tuberculosis is correct. Silica impairs macrophage phagolysosome function and predisposes to tuberculosis. Upper lobe nodules and eggshell calcifications strongly suggest silicosis. Ver explicação completa e trilha adaptativa →