A 45-year-old woman with no prior medical history presents to the emergency department 4 hours after a motor vehicle accident with crush injuries to both lower extremities. On examination, she has severe swelling and bruising of both legs with preserved distal pulses. Vital signs show HR 112 bpm, BP 95/58 mmHg, RR 22/min. Laboratory studies reveal: serum creatinine 3.2 mg/dL (baseline 0.9 mg/dL), BUN 48 mg/dL, potassium 6.1 mEq/L, urine color dark brown. Urinalysis shows specific gravity 1.035, dipstick positive for blood with 0 RBCs on microscopy, and positive myoglobin. Urine osmolality is 620 mOsm/kg. Which of the following is the most appropriate immediate intervention?
- A)Initiate hemodialysis for acute hyperkalemia management
- B)Administer aggressive intravenous hydration with normal saline and target urine output 200-300 mL/hourGABARITO
- C)Administer sodium bicarbonate 1-2 mEq/kg IV to alkalinize urine
- D)Administer furosemide 40 mg IV to promote diuresis and reduce fluid overload
- E)Perform bilateral fasciotomy to decompress leg compartments
Explicação
This patient has rhabdomyolysis-induced acute kidney injury (AKI) from crush injury with classic findings: myoglobinuria (dark urine, positive dipstick blood without RBCs), hyperkalemia, and rapidly rising creatinine in the setting of trauma. The pathophysiolo... Ver explicação completa e trilha adaptativa →