A 27-year-old woman with a 12-year history of type 1 diabetes mellitus presents to her endocrinologist for a routine follow-up. She currently uses a basal bolus insulin regimen with insulin glargine at bedtime and regular insulin before meals. Her fasting glucose values have been well-controlled, averaging 95–105 mg/dL, but she reports consistent postprandial glucose spikes to 280–320 mg/dL occurring approximately 30–60 minutes after eating. Her hemoglobin A1c is 8.4%, and her BMI is 22 kg/m². Vital signs are within normal limits. Physical examination reveals no lipodystrophy at injection sites. Her physician decides to switch her mealtime insulin to a preparation with a faster onset and shorter duration of action that should be injected immediately before eating. Which of the following drugs was most likely prescribed?
- A)Regular insulin
- B)NPH insulin
- C)Insulin glargine
- D)Insulin degludec
- E)Insulin lisproGABARITO
Explicação
Insulin lispro is a rapid acting insulin analog used for prandial coverage. It has very fast onset and short duration, making it appropriate for immediate premeal dosing to blunt postprandial glucose excursions while preserving basal control from the patient’s... Ver explicação completa e trilha adaptativa →