A 31 year old woman presents with blurry vision in her right eye and pain with eye movement for 2 days. Six months ago she had transient numbness of the left leg that resolved spontaneously. Examination shows decreased visual acuity in the right eye and an afferent pupillary defect. MRI of the brain shows multiple periventricular plaques. Which of the following is the most likely diagnosis?

  1. A)Multiple sclerosisGABARITO
  2. B)Acute inflammatory demyelinating polyradiculoneuropathy
  3. C)Neuromyelitis optica due to peripheral nerve demyelination
  4. D)Subacute combined degeneration
  5. E)Progressive supranuclear palsy

Explicação

Multiple sclerosis is correct. Relapsing neurologic deficits separated in time and space, optic neuritis, and periventricular white matter plaques are classic for autoimmune CNS demyelination. The disease is mediated by autoreactive T cells against myelin, oft... Ver explicação completa e trilha adaptativa →

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