A 35-year-old woman with newly diagnosed hypertension and hypokalemia undergoes screening. Serum aldosterone is 18 ng/dL with plasma renin activity of 0.8 ng/mL/hr. Aldosterone-to-renin ratio is 22.5. Saline infusion test shows persistent aldosterone elevation (14 ng/dL). Bilateral adrenal CT is normal. Which of the following is the most likely diagnosis?
- A)Secondary hyperaldosteronism from renal disease
- B)Adrenal carcinoma
- C)Glucocorticoid-remediable aldosteronism
- D)Aldosterone-producing adenoma
- E)Idiopathic hyperaldosteronismGABARITO
Explicação
Idiopathic hyperaldosteronism (IHA) presents with elevated aldosterone-to-renin ratio and mild to moderate hypokalemia but no identifiable adenoma on imaging. It may represent bilateral micronodular hyperplasia. Saline suppression does not fully suppress aldos... Ver explicação completa e trilha adaptativa →