A 52-year-old man presents with acute onset severe headache, profuse diaphoresis, palpitations, and blood pressure of 185/110 mmHg. His symptoms are episodic, lasting 30-60 minutes. Plasma metanephrines are elevated. An abdominal CT reveals a 3.2 cm right adrenal mass. Which of the following is the most appropriate next step in management?

  1. A)Initiate alpha-blockade followed by beta-blockade, then surgical resectionGABARITO
  2. B)Perform adrenal biopsy for histologic confirmation
  3. C)Start hydralazine and schedule a repeat CT in 3 months
  4. D)Immediate surgical resection without pharmacologic preparation
  5. E)Begin beta-blockade alone followed by surgery

Explicação

This patient has pheochromocytoma with classic catecholamine-induced hypertensive crisis. Before surgery, alpha-blockade (phenoxybenzamine) must be given first to prevent severe hypertensive episodes intraoperatively. Beta-blockade is then added (only after al... Ver explicação completa e trilha adaptativa →

Fazer o diagnóstico grátis de USMLE