A 58-year-old diabetic man with end-stage renal disease on hemodialysis presents with a non-healing ulcer on his left foot and progressive toe gangrene. Vital signs show BP 158/92 mmHg, HR 88/min, and normal SpO2. Pedal pulses are diminished but palpable bilaterally. Ankle-brachial index is 1.3 bilaterally. Serum calcium is 9.8 mg/dL with elevated phosphate. Duplex ultrasound reveals no significant stenosis. Which vascular pathology best explains these findings?

  1. A)Atherosclerotic intimal plaque with lipid core
  2. B)Thromboangiitis obliterans with inflammation
  3. C)Vasculitis from polyarteritis nodosa
  4. D)Mönckeberg sclerosis with medial calcificationGABARITO
  5. E)Arterial dissection with intramural hematoma

Explicação

Mönckeberg sclerosis (medial calcific sclerosis) presents with ABI >1.1-1.3 due to rigid calcified vessels that cannot compress. It is characteristic in diabetics with ESRD on dialysis, causing tissue ischemia despite palpable pulses. Ver explicação completa e trilha adaptativa →

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