A 27-year-old man presents with abrupt-onset, involuntary jerky movements of his face and distal extremities. His father died after years of progressive abnormal movements and cognitive decline. Vital signs: BP 118/76, HR 88, RR 16, temp 37°C, SpO2 98%. MRI demonstrates caudate nucleus atrophy. Serum copper and ceruloplasmin levels are normal. He denies recent antipsychotic use. Which of the following is the most likely diagnosis?
- A)Huntington diseaseGABARITO
- B)Restless legs syndrome
- C)Parkinson disease
- D)Dystonia
- E)Essential tremor
Explicação
Huntington disease is an autosomal dominant trinucleotide repeat disorder causing loss of GABAergic neurons in the striatum with chorea, psychiatric changes, and dementia. Ver explicação completa e trilha adaptativa →