A 43-year-old woman who breeds pigeons presents with intermittent fever (38.2°C), cough, and dyspnea developing several hours after cleaning bird cages. Vital signs show HR 102, RR 24, SpO2 88% on room air. Fine crackles are audible bilaterally. Chest imaging demonstrates diffuse ground-glass interstitial infiltrates. Spirometry shows a restrictive pattern. She denies recent antibiotic use. Which of the following best describes the underlying mechanism of her pulmonary pathology?
- A)Immune mediated alveolar and interstitial inflammation from inhaled organic antigensGABARITO
- B)Direct angioinvasion by Aspergillus hyphae
- C)Deposition of ferruginous bodies within the pleura
- D)Suppurative destruction of bronchi due to cystic fibrosis
- E)Type I hypersensitivity with mast cell degranulation only
Explicação
Immune mediated alveolar and interstitial inflammation from inhaled organic antigens is correct. Hypersensitivity pneumonitis is caused by repeated exposure to inhaled antigens such as bird proteins or mold, producing an immune reaction in the alveoli and inte... Ver explicação completa e trilha adaptativa →