A 22-year-old man presents with recurrent episodes of generalized weakness beginning after rest following strenuous exercise. Episodes last 20-45 minutes and are associated with mild myotonia. Vital signs show HR 78/min, BP 128/82 mmHg, RR 16/min, temperature 37°C, SpO2 98%. Serum potassium is 5.8 mEq/L during an acute attack. Creatine kinase is normal. He denies recent medication use or similar family history. Which of the following is the most likely diagnosis?

  1. A)Polymyositis
  2. B)Botulism
  3. C)Lambert-Eaton syndrome
  4. D)ALS
  5. E)Hyperkalemic periodic paralysisGABARITO

Explicação

Hyperkalemic periodic paralysis is due to a skeletal muscle sodium channel abnormality that causes transient weakness associated with elevated potassium during attacks. Episodes are often brief and may follow rest after exercise. Ver explicação completa e trilha adaptativa →

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