A 38-year-old man with untreated HIV presents with progressive dyspnea, nonproductive cough, and fever for 3 weeks. Vitals: BP 118/76, HR 102, RR 24, Temp 38.5°C, SpO2 88% on room air. CD4 count is 88 cells/mm³. Serum LDH is 425 U/L (elevated). Chest X-ray shows diffuse bilateral interstitial infiltrates. Sputum cultures are negative. He takes no antiretroviral medications. Which of the following is the best treatment?
- A)Ceftriaxone
- B)Oseltamivir
- C)Trimethoprim sulfamethoxazoleGABARITO
- D)Isoniazid rifampin pyrazinamide ethambutol
- E)Azithromycin
Explicação
Pneumocystis jirovecii pneumonia is an opportunistic infection seen in advanced HIV, often when the CD4 count is below 200. It causes progressive hypoxemia, diffuse interstitial infiltrates, and elevated LDH, and it is treated with trimethoprim sulfamethoxazol... Ver explicação completa e trilha adaptativa →