A 58-year-old man presents with a painful violaceous scalp mass that developed 8 years after radiation therapy for brain lymphoma. Vital signs show BP 138/82, HR 88, RR 16, Temp 37.2°C, SpO2 98%. Physical examination reveals a 3-cm indurated nodule with surrounding edema. Biopsy demonstrates a malignant vascular neoplasm with high mitotic activity. Imaging shows no osseous involvement. Which immunohistochemical stain most likely confirms the diagnosis?
- A)PSA
- B)PECAM 1 CD31GABARITO
- C)TRAP
- D)Neurofilament
- E)GFAP
Explicação
Angiosarcoma is a malignant vascular tumor and typically expresses endothelial markers such as PECAM 1, also known as CD31. This stain supports endothelial differentiation in a tumor suspected to arise from blood vessels. Ver explicação completa e trilha adaptativa →