A 6-year-old boy presents with a 1-week history of abdominal pain, arthralgia, and palpable purpura on his buttocks and lower extremities. Vital signs show BP 118/76 mmHg, HR 98/min, RR 22/min, and temperature 37.2°C. Urinalysis reveals microscopic hematuria and mild proteinuria (1+). Serum creatinine is 0.8 mg/dL. Blood cultures are negative. Platelet count is normal. Which renal histopathologic lesion is most likely present?
- A)Subepithelial immune complex humps
- B)Diffuse podocyte foot process effacement
- C)Mesangial IgA depositionGABARITO
- D)Linear IgG deposition on the glomerular basement membrane
- E)Nodular mesangial sclerosis
Explicação
IgA vasculitis, formerly called Henoch Schonlein purpura, is a small-vessel vasculitis characterized by palpable purpura, arthralgias, abdominal pain, and renal involvement. The kidney lesion mirrors IgA nephropathy, with mesangial IgA deposition causing hemat... Ver explicação completa e trilha adaptativa →