A 2-week-old male infant born to a mother with untreated systemic lupus erythematosus presents with poor feeding and hepatomegaly. Vital signs show heart rate of 55 bpm, blood pressure 65/40 mmHg, respiratory rate 32/min, temperature 37.2°C, and SpO2 98% on room air. Electrocardiography demonstrates a prolonged PR interval progressing to complete heart block. Maternal anti-Ro/SSA antibodies are positive. The infant denies cyanosis. Which of the following is the most likely diagnosis?
- A)Congenital heart block from maternal anti-Ro/SSA antibodiesGABARITO
- B)Myocarditis from viral infection
- C)Congenital syphilis
- D)Lyme disease from in utero transmission
- E)Atrioventricular canal defect
Explicação
Maternal anti-Ro/SSA and anti-La/SSB antibodies from lupus or Sjögren syndrome cross the placenta and damage the fetal atrioventricular node, causing congenital heart block. This typically manifests as progressive PR prolongation to complete heart block in ute... Ver explicação completa e trilha adaptativa →