A 34-year-old woman presents with sudden-onset polyarthralgias, fever, and a painful erythematous rash on her lower extremities. Vital signs show temperature 38.5°C, heart rate 102/min, blood pressure 128/82 mmHg, and SpO2 98% on room air. Skin biopsy demonstrates leukocytoclasia with fibrinoid necrosis of small blood vessels. Laboratory studies reveal elevated ESR and normal complement levels. She denies recent upper respiratory infection. Which of the following is the most likely diagnosis?
- A)IgA vasculitisGABARITO
- B)Systemic lupus erythematosus
- C)Granulomatosis with polyangiitis
- D)Hypersensitivity vasculitis
- E)Polyarteritis nodosa
Explicação
IgA vasculitis (formerly Henoch-Schönlein purpura) is a small-vessel vasculitis characterized by IgA immune complex deposition and leukocytoclasia with fibrinoid necrosis. Classic presentation includes palpable purpura on lower extremities, arthritis, and abdo... Ver explicação completa e trilha adaptativa →