A 61 year old man presents with gross hematuria, weight loss, and dull flank pain. He has a 40 pack year smoking history. Examination reveals a left sided varicocele that does not decrease when he lies supine. CT scan shows a mass arising from the upper pole of the left kidney. Which of the following paraneoplastic findings is most likely associated with this tumor?
- A)Erythrocytosis due to ectopic erythropoietin productionGABARITO
- B)Watery diarrhea due to VIP secretion
- C)Cushing syndrome due to ACTH deficiency
- D)Hypocalcemia due to low vitamin D
- E)Hyperglycemia due to glucagon secretion
Explicação
Erythrocytosis due to ectopic erythropoietin production is correct. Renal cell carcinoma arises from renal tubular epithelium and can produce paraneoplastic syndromes including erythropoietin, PTH related peptide, ACTH, or renin secretion. Smoking, hematuria, ... Ver explicação completa e trilha adaptativa →