A full term newborn develops profound cyanosis within hours of birth. The infant of a mother with poorly controlled diabetes remains severely hypoxemic despite supplemental oxygen. Echocardiography shows the aorta arising from the right ventricle and the pulmonary artery arising from the left ventricle. Which of the following is the most appropriate initial pharmacologic intervention?
- A)Ibuprofen
- B)Epinephrine
- C)Furosemide
- D)Prostaglandin E1 infusionGABARITO
- E)Indomethacin
Explicação
Prostaglandin E1 infusion is correct. This neonate has transposition of the great arteries, which creates parallel rather than series circulation and requires mixing of blood through a PDA, ASD, or VSD for survival. Prostaglandin E1 keeps the ductus arteriosus... Ver explicação completa e trilha adaptativa →