A 57 year old woman with a 20 year history of type 2 diabetes mellitus comes for follow up. She has diabetic retinopathy and peripheral neuropathy. Urine albumin excretion has progressively increased over the past several years, and she now has edema and declining renal function. Renal biopsy would most likely show which of the following findings?
- A)Mesangial IgA deposition
- B)Kimmelstiel Wilson nodulesGABARITO
- C)Crescent formation with linear IgG staining
- D)Normal light microscopy with foot process effacement
- E)Subepithelial humps
Explicação
Kimmelstiel Wilson nodules are correct. Long standing diabetes causes nonenzymatic glycosylation, mesangial expansion, glomerular basement membrane thickening, and nodular glomerulosclerosis. Progressive albuminuria in a patient with other diabetic microvascul... Ver explicação completa e trilha adaptativa →