A 34-year-old man presents with difficulty releasing his grip after handshaking. He reports early frontal balding and recent cataracts. Vital signs are stable: BP 128/82, HR 78, RR 16, Temp 37°C, SpO2 98%. Physical examination reveals myotonia. Laboratory studies show elevated creatine kinase at 850 IU/L. He denies recent medication use or muscle pain. Which of the following is the most likely diagnosis?
- A)Dermatomyositis
- B)Myotonic dystrophyGABARITO
- C)Duchenne muscular dystrophy
- D)Lambert-Eaton syndrome
- E)Polymyalgia rheumatica
Explicação
Myotonic dystrophy causes delayed muscle relaxation, classically difficulty releasing grip, along with systemic findings such as cataracts, frontal balding, gonadal atrophy, and cardiac conduction defects. It is due to a trinucleotide repeat expansion disorder... Ver explicação completa e trilha adaptativa →