A 35-year-old man presents with gross hematuria and flank pain one week after an upper respiratory infection. Vital signs: BP 128/82 mmHg, HR 88/min, RR 16/min, Temp 37.2°C, SpO2 98%. Urinalysis reveals RBC casts and dysmorphic RBCs; serum creatinine is 0.9 mg/dL (normal). Throat culture is negative. Kidney biopsy demonstrates predominant IgA deposition on immunofluorescence microscopy with mesangial proliferation on light microscopy. Which of the following is the most likely diagnosis?
- A)Lupus nephritis
- B)Post-infectious glomerulonephritis
- C)Rapidly progressive glomerulonephritis
- D)IgA nephropathyGABARITO
- E)Alport syndrome
Explicação
IgA nephropathy is the most common primary glomerulonephritis worldwide, characterized by predominant IgA immune complex deposition. Classic presentation includes hematuria following URI, RBC casts, dysmorphic RBCs, and normal or near-normal renal function at ... Ver explicação completa e trilha adaptativa →