A 31-year-old pregnant woman at 26 weeks gestation presents with fatigue and polyuria. Vital signs: BP 118/76 mmHg, HR 88/min, RR 16/min, temp 37°C. Fasting glucose is 126 mg/dL; HbA1c is 6.2%. She denies gestational diabetes history and takes prenatal vitamins only. Previous glucose tolerance testing before pregnancy was normal. Which hormone produced during pregnancy most directly contributes to the insulin resistance observed in this patient?
- A)Human placental lactogenGABARITO
- B)TSH
- C)Prolactin from the posterior pituitary
- D)Oxytocin
- E)Progesterone from the corpus luteum only
Explicação
Human placental lactogen increases during pregnancy and promotes insulin resistance, helping ensure nutrient availability for the fetus. In susceptible patients this can unmask gestational diabetes, especially later in pregnancy when placental hormone levels a... Ver explicação completa e trilha adaptativa →