A 45-year-old woman presents with progressive fatigue, weight gain of 8 kg over 3 months, constipation, and cold intolerance. Vital signs show BP 128/82 mmHg, HR 58 bpm, RR 14/min, temperature 36.2°C. Examination reveals a painless, firm, diffusely enlarged thyroid gland without nodules. Laboratory studies demonstrate TSH 12.5 mIU/L (elevated), free T4 0.6 ng/dL (low), and positive anti-thyroid peroxidase antibodies. Thyroid ultrasound shows homogeneous echotexture. She denies recent iodine exposure. Which of the following is the most likely diagnosis?
- A)Medullary thyroid carcinoma
- B)Toxic multinodular goiter
- C)Hashimoto thyroiditisGABARITO
- D)Subacute granulomatous thyroiditis
- E)Graves disease
Explicação
Hashimoto thyroiditis is an autoimmune destruction of the thyroid characterized by anti thyroid peroxidase and anti thyroglobulin antibodies. Patients usually present with hypothyroidism and a painless goiter. Histologically there is lymphoid aggregation with ... Ver explicação completa e trilha adaptativa →