A 41-year-old man presents with an 8-month history of decreased libido, erectile dysfunction, and progressive headaches. Vital signs show BP 138/82, HR 78, RR 16, temp 37.2°C, SpO2 98%. Examination reveals bilateral gynecomastia and bitemporal hemianopia. Visual acuity remains intact. MRI demonstrates a 1.8 cm sellar mass with elevated prolactin level at 180 ng/mL. Which cell type most likely gave rise to this lesion?
- A)Somatotroph
- B)Thyrotroph
- C)Corticotroph
- D)LactotrophGABARITO
- E)Gonadotroph
Explicação
A prolactinoma arises from lactotroph cells of the anterior pituitary. Excess prolactin suppresses hypothalamic GnRH, leading to low LH and testosterone, which explains the erectile dysfunction and gynecomastia. The large tumor also compresses the optic chiasm... Ver explicação completa e trilha adaptativa →