A 63-year-old woman is hospitalized for acute pulmonary embolism with HR 118/min, BP 136/88 mmHg, RR 22/min, and SpO2 88% on room air. She is started on intravenous anticoagulation. Her aPTT, previously 28 seconds, is now 67 seconds within 2 hours. Troponin is mildly elevated. She denies previous heparin exposure. The medication works by potentiating antithrombin activity against thrombin and factor Xa. Which anticoagulant was most likely administered?
- A)HeparinGABARITO
- B)Apixaban
- C)Aspirin
- D)Warfarin
- E)Clopidogrel
Explicação
Heparin potentiates antithrombin, causing rapid inhibition of thrombin and factor Xa. Its effect is monitored with activated partial thromboplastin time and it is commonly used acutely for venous thromboembolism. Ver explicação completa e trilha adaptativa →