A 41-year-old man presents with hypertension (BP 158/96 mmHg, HR 88/min) and bilateral flank fullness. His father required dialysis at age 52. Physical examination reveals palpable kidneys bilaterally; no edema noted. Serum creatinine is 1.8 mg/dL with eGFR of 42 mL/min/1.73m². Urinalysis shows microscopic hematuria without proteinuria. Renal ultrasound demonstrates numerous bilateral cysts of varying sizes with normal echotexture between cysts. Which of the following additional findings is most strongly associated with this condition?
- A)Bilateral sensorineural hearing loss with ocular defects
- B)Berry aneurysm in the circle of WillisGABARITO
- C)Biconcave red blood cells in the urine
- D)Wilms tumor arising from nephroblastoma tissue
- E)Congenital hepatic fibrosis presenting in infancy
Explicação
Autosomal dominant polycystic kidney disease is associated with renal cyst enlargement, hypertension, hematuria, hepatic cysts, mitral valve prolapse, and intracranial berry aneurysms. A family history of adult onset renal failure with bilateral cysts is highl... Ver explicação completa e trilha adaptativa →